Differentiate acute toxicity studies from chronic toxicity studies and name typical endpoints.

• A. Acute toxicity studies examine long-term effects; chronic toxicity studies are short-term.
• B. Acute toxicity studies assess effects after short-term or single exposure; chronic toxicity studies assess long-term effects (months/years) with endpoints such as organ injury, tumors, reproductive outcomes, and survival.
• C. Endpoints only include mortality for both.
• D. Acute toxicity uses chemo endpoints; chronic uses only behavioral endpoints.

Answer: (B)