Explain dermal bioavailability and factors that influence dermal absorption.

• A. Dermal bioavailability is the fraction of a dermal-applied dose that reaches systemic circulation; influenced by formulation, vehicle, skin integrity, occlusion, surface area, and compound properties.
• B. Dermal bioavailability is the rate at which a chemical evaporates from the skin surface.
• C. Dermal bioavailability refers to the percentage of people who develop systemic effects after dermal exposure.
• D. Dermal bioavailability is identical to the total amount of chemical present on the skin.

Answer: (A)