Inhalation toxicology assessments primarily evaluate deposition in the lungs and related endpoints. Which statement best describes inhalation endpoints?

• A. Exposure is limited to the skin with no pulmonary effects.
• B. Inhalation assessments only measure local airway irritation, not systemic effects.
• C. Exposure involves deposition in the lungs, absorption via the lungs, airway irritation, and systemic effects.
• D. Inhalation assessments ignore nasal passages.

Answer: (C)